CLK2P1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLK2P1 mutation is significantly associated with the immune_cell of many other genes, with 13 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CLK2P1-associated genes across cancer lineages are Endothelial cells, Th2 cells, and Monocytes. Each is linked with CLK2P1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLK2P1-to-partner and partner-to-CLK2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by CLK2P1-low versus CLK2P1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLK2P1→partner) and Y-score (partner→CLK2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMEndothelial cells →-0.039-2.064.003.00132
COADTh2 cells →+0.200+3.000.035.03714
OVMonocytes →+0.025+5.507<.001.04232
SKCMlymphatic Endothelial cells →-0.016-3.250.027.00631
SKCMmv Endothelial cells →-0.024-3.521.007.00231
SKCMMyocytes →+0.038+1.954.002.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Endothelial cells by CLK2P1 expression — SKCM

Box plot of Endothelial cells in CLK2P1-low vs CLK2P1-high samples in SKCM.

Explore this box plot interactively →

Exploration