CLK1

Across TCGA patient cohorts, CLK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,630 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CLK1-associated proteins across cancer lineages are ABI2, PPIF, and RPL21. Each is linked with CLK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLK1-to-partner and partner-to-CLK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLK1 versus ABI2 in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLK1→partner) and Y-score (partner→CLK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABI2 →	+0.467	+0.498	<.001	<.001	3	6
LSCC	PPIF →	-0.463	-0.356	.002	.002	3	5
BRCA	RPL21 →	-0.221	-0.629	.004	<.001	3	5
BRCA	RPS8 →	-0.243	-0.635	<.001	<.001	3	5
BRCA	HDGFL3 →	+0.566	+0.493	<.001	<.001	3	5
BRCA	EHD2_S438 →	+1.019	+0.777	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,630 associations by consensus.

CLK1 vs ABI2 — LSCC

Explore this scatter interactively →