CLK1

Across TCGA cell cohorts, CLK1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLK1-associated genes across cancer lineages are FAM25C and OR10W1. Each is linked with CLK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLK1-to-partner and partner-to-CLK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM25C grouped by CLK1-low versus CLK1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLK1→partner) and Y-score (partner→CLK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FAM25C →	+0.351	+5.209	<.001	.005	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FAM25C by CLK1 expression — BLOOD_Lymphoma

Explore this box plot interactively →