CLIP4

Across TCGA patient cohorts, CLIP4 protein abundance is significantly associated with the RNA expression of many other genes, with 3,811 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLIP4-associated genes across cancer lineages are FBXW7, LDB3, and FAM171A1. Each is linked with CLIP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLIP4-to-partner and partner-to-CLIP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLIP4 versus FBXW7 in OV, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIP4→partner) and Y-score (partner→CLIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FBXW7 →	+0.704	+1.246	<.001	.003	3	2
GBM	LDB3 →	+0.889	+0.363	<.001	<.001	3	2
OV	FAM171A1 →	+0.988	+1.246	.006	.003	3	2
OV	SLC13A4 →	+0.784	+1.160	.002	.007	3	2
OV	TVP23A →	+1.330	+1.748	.003	.004	3	2
OV	PAQR8 →	+1.110	+1.304	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,811 associations by consensus.

CLIP4 vs FBXW7 — OV

Explore this scatter interactively →