CLIP4

Across TCGA cell cohorts, CLIP4 mutation is significantly associated with the RNA expression of many other genes, with 138 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLIP4-associated genes across cancer lineages are GCAT, VAPA, and C1QBP. Each is linked with CLIP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLIP4-to-partner and partner-to-CLIP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by CLIP4-low versus CLIP4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIP4→partner) and Y-score (partner→CLIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.474	+3.212	<.001	.006	3	1
LARGE_INTESTINE	VAPA →	+0.550	+3.212	.005	.006	3	1
LARGE_INTESTINE	C1QBP →	+0.919	+3.301	<.001	.003	3	1
LARGE_INTESTINE	RPAP2 →	+0.862	+3.212	<.001	.006	3	1
LARGE_INTESTINE	ELP2 →	+0.811	+3.212	<.001	.006	3	1
LARGE_INTESTINE	MYG1 →	+0.315	+3.212	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 138 associations by consensus.

GCAT by CLIP4 expression — LARGE_INTESTINE

Explore this box plot interactively →