CLIP3

Across TCGA cell cohorts, CLIP3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLIP3-associated genes across cancer lineages are OR2M4, OR2H1, and OR2L8. Each is linked with CLIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLIP3-to-partner and partner-to-CLIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M4 grouped by CLIP3-low versus CLIP3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIP3→partner) and Y-score (partner→CLIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2M4 →	+0.070	+4.700	<.001	.002	3	1
OVARY	OR2H1 →	+0.019	+4.029	.003	.009	3	1
OVARY	OR2L8 →	+0.038	+4.450	<.001	.004	3	1
SKIN	ZNF705G →	+0.027	+4.467	<.001	.004	3	1
BREAST	OR2G6 →	+0.016	+5.169	<.001	.005	3	1
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

OR2M4 by CLIP3 expression — OVARY

Explore this box plot interactively →