CLIP2

Across TCGA patient cohorts, CLIP2 mutation is significantly associated with the RNA expression of many other genes, with 4,951 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLIP2-associated genes across cancer lineages are SLC2A13, TSPY26P, and GARS1P1. Each is linked with CLIP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLIP2-to-partner and partner-to-CLIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC2A13 grouped by CLIP2-low versus CLIP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIP2→partner) and Y-score (partner→CLIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC2A13 →	+0.282	+1.764	.004	.001	3	4
COAD	TSPY26P →	-0.837	-3.432	<.001	.005	3	4
BRCA	GARS1P1 →	+0.044	+3.883	<.001	.002	3	3
UCEC	LACTB →	+0.523	+1.960	<.001	<.001	3	3
COAD	ULBP2 →	+0.983	+3.469	.001	.002	3	3
COAD	ATP9A →	-1.121	-3.807	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,951 associations by consensus.

SLC2A13 by CLIP2 expression — UCEC

Explore this box plot interactively →