CLIP1

Across TCGA patient cohorts, CLIP1 mutation is significantly associated with the RNA expression of many other genes, with 3,707 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLIP1-associated genes across cancer lineages are CALM1, NOP10, and SETD3. Each is linked with CLIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CLIP1-to-partner and partner-to-CLIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CALM1 grouped by CLIP1-low versus CLIP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIP1→partner) and Y-score (partner→CLIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CALM1 →	+0.368	+2.566	.001	.009	3	3
UCEC	NOP10 →	+0.509	+2.237	<.001	<.001	3	3
UCEC	SETD3 →	+0.386	+3.191	<.001	<.001	3	3
UCEC	AJM1 →	+0.368	+2.534	.003	<.001	3	3
UCEC	GSKIP →	+0.416	+3.000	<.001	<.001	3	3
UCEC	PSMB7 →	+0.319	+1.837	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,707 associations by consensus.

CALM1 by CLIP1 expression — COAD

Explore this box plot interactively →