CLIP1

Across TCGA cell cohorts, CLIP1 mutation is significantly associated with the RNA expression of many other genes, with 129 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLIP1-associated genes across cancer lineages are OR2V2, PNLIPRP3, and CR2. Each is linked with CLIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLIP1-to-partner and partner-to-CLIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2V2 grouped by CLIP1-low versus CLIP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIP1→partner) and Y-score (partner→CLIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR2V2 →	+0.035	+2.354	.001	.008	3	2
STOMACH	PNLIPRP3 →	+0.128	+3.432	.005	.008	3	2
LARGE_INTESTINE	CR2 →	+1.082	+3.184	<.001	.007	3	2
LUNG_NSCLC_LUAD	TEX53 →	+0.127	+3.786	<.001	.001	3	2
BLOOD_Leukemia	C6orf118 →	+0.031	+3.035	<.001	<.001	3	2
LUNG_NSCLC_LUSC	CCDC140 →	+0.083	+4.643	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

OR2V2 by CLIP1 expression — BLOOD_Leukemia

Explore this box plot interactively →