CLINT1

Across TCGA patient cohorts, CLINT1 mutation is significantly associated with the RNA expression of many other genes, with 2,127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLINT1-associated genes across cancer lineages are LINC02559, RNA5SP410, and RNA5SP413. Each is linked with CLINT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLINT1-to-partner and partner-to-CLINT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by CLINT1-low versus CLINT1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLINT1→partner) and Y-score (partner→CLINT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
CESC	RNA5SP410 →	+0.590	+5.569	<.001	.002	3	2
CESC	RNA5SP413 →	+0.380	+7.174	<.001	<.001	3	2
UCEC	RNA5SP417 →	+0.635	+2.434	<.001	<.001	3	2
CESC	RNA5SP73 →	+0.332	+5.837	<.001	.001	3	2
UCEC	RNA5SP422 →	+0.830	+1.753	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,127 associations by consensus.

LINC02559 by CLINT1 expression — CESC

Explore this box plot interactively →