CLINT1

Across TCGA cell cohorts, CLINT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,216 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLINT1-associated GO terms across cancer lineages are Regulation of translational initiation, Metaphase/anaphase transition of mitotic cell cycle, and Establishment of protein localization to organelle. Each is linked with CLINT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CLINT1-to-partner and partner-to-CLINT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by CLINT1-low versus CLINT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLINT1→partner) and Y-score (partner→CLINT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.083	+1.072	.002	.001	3	14
OESOPHAGUS	Metaphase/anaphase transition of mitotic cell cycle →	+0.178	+0.826	<.001	.004	3	14
CNS	Establishment of protein localization to organelle →	+0.051	+0.533	<.001	<.001	3	13
OESOPHAGUS	Post-transcriptional gene silencing →	+0.130	+0.836	<.001	<.001	3	13
BLOOD_Lymphoma	Regulatory ncRNA-mediated gene silencing →	+0.064	+1.223	<.001	<.001	3	13
OESOPHAGUS	Metaphase/anaphase transition of cell cycle →	+0.176	+0.875	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,216 associations by consensus.

Regulation of translational initiation by CLINT1 expression — UPPER_AERODIGESTIVE_TRACT

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