CLIC6

Across TCGA cell cohorts, CLIC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,247 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CLIC6-associated GO terms across cancer lineages are Spermatid differentiation, Striated muscle contraction, and Spermatid development. Each is linked with CLIC6 in more than 6 cancer types. Because this analysis shows association rather than direction, both CLIC6-to-partner and partner-to-CLIC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spermatid differentiation grouped by CLIC6-low versus CLIC6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC6→partner) and Y-score (partner→CLIC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Spermatid differentiation →	-0.024	-0.929	<.001	.006	2	7
BLOOD_Lymphoma	Striated muscle contraction →	+0.042	+0.773	<.001	.003	3	6
BLOOD_Lymphoma	Spermatid development →	-0.021	-0.879	.003	.008	2	7
SOFT_TISSUE	Protein targeting to membrane →	+0.056	+0.355	<.001	.005	3	6
BLOOD_Lymphoma	Sperm flagellum assembly →	-0.024	-0.565	.002	.003	3	5
BLOOD_Lymphoma	Energy derivation by oxidation of organic compounds →	+0.040	+0.598	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,247 associations by consensus.

Spermatid differentiation by CLIC6 expression — BLOOD_Lymphoma

Explore this box plot interactively →