CLIC3

Across TCGA cell cohorts, CLIC3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CLIC3-associated genes across cancer lineages are CHIA and RBMY1J. Each is linked with CLIC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLIC3-to-partner and partner-to-CLIC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHIA grouped by CLIC3-low versus CLIC3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC3→partner) and Y-score (partner→CLIC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CHIA →	+1.476	+5.087	<.001	.004	3	1
OVARY	RBMY1J →	+0.023	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CHIA by CLIC3 expression — URINARY_TRACT

Explore this box plot interactively →