Across TCGA patient cohorts, CLIC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLIC1-associated proteins across cancer lineages are CD2AP, ABCD1, and HSP90AB1. Each is linked with CLIC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CLIC1-to-partner and partner-to-CLIC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC1→partner) and Y-score (partner→CLIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD2AP →	+0.498	+0.658	<.001	<.001	3	5
GBM	ABCD1 →	+0.498	+0.718	<.001	.001	3	5
PDAC	HSP90AB1 →	+0.264	+0.433	<.001	.001	3	5
GBM	SERPINB1 →	+0.583	+0.763	<.001	<.001	3	5
LUAD	CCDC6_S52 →	+0.747	+0.362	.001	.002	3	4
OV	ABCF1 →	+0.207	+0.420	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,126 associations by consensus.

Exploration

CLIC1 survival (RNA) · tumor vs normal (RNA) · all CLIC1 data types