Across TCGA cell cohorts, CLIC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,962 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLIC1-associated GO terms across cancer lineages are Low-density lipoprotein particle clearance, Calcium ion homeostasis, and Actin filament organization. Each is linked with CLIC1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CLIC1-to-partner and partner-to-CLIC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC1→partner) and Y-score (partner→CLIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Low-density lipoprotein particle clearance →	+0.164	+1.256	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Calcium ion homeostasis →	+0.094	+0.782	<.001	<.001	3	11
BONE	Actin filament organization →	+0.142	+1.008	<.001	<.001	3	11
LUNG_SCLC	Death-inducing signaling complex assembly →	+0.307	+0.934	.006	.003	3	11
BONE	Integrin-mediated signaling pathway →	+0.263	+0.888	<.001	<.001	3	11
LIVER	Regulation of collagen biosynthetic process →	+0.234	+1.251	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,962 associations by consensus.

Exploration

CLIC1 survival (RNA) · tumor vs normal (RNA) · all CLIC1 data types