CLEC9A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLEC9A mutation is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC9A-associated genes across cancer lineages are OR2AP1, RNU6-623P, and RNU7-143P. Each is linked with CLEC9A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC9A-to-partner and partner-to-CLEC9A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC9A→partner) and Y-score (partner→CLEC9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOR2AP1 →+0.040+2.977.007.00932
UCECRNU6-623P →+0.444+2.050.001.00732
BRCARNU7-143P →+0.615+6.442<.001.00132
BRCAMIR4267 →+0.460+7.725<.001<.00132
UCECCHAF1A →+0.635+2.606.004.00632
UCECHASPIN →+0.849+2.593.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

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