Across TCGA patient cohorts, CLEC9A mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC9A-associated genes across cancer lineages are Caspase-7-cleavedD198, MSH2, and ATM. Each is linked with CLEC9A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC9A-to-partner and partner-to-CLEC9A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC9A→partner) and Y-score (partner→CLEC9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.712	+3.189	.013	.010	3	2
UCEC	MSH2 →	-0.321	-2.973	.003	.035	3	1
UCEC	ATM →	-0.522	-3.000	.017	.036	3	1
LUAD	SF2 →	-0.154	-3.000	.012	.036	2	1
UCEC	eEF2 →	+0.363	+2.459	.035	.020	2	1
UCEC	GATA6 →	-0.187	-2.314	.016	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

CLEC9A survival (RNA) · tumor vs normal (RNA) · all CLEC9A data types