CLEC7A

Across TCGA patient cohorts, CLEC7A mutation is significantly associated with the RNA expression of many other genes, with 1,798 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC7A-associated genes across cancer lineages are BSNDP1, RNA5SP411, and MIR513C. Each is linked with CLEC7A in more than 2 cancer types. Because this analysis shows association rather than direction, both CLEC7A-to-partner and partner-to-CLEC7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BSNDP1 grouped by CLEC7A-low versus CLEC7A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC7A→partner) and Y-score (partner→CLEC7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	BSNDP1 →	+0.277	+7.307	<.001	<.001	3	3
UCEC	RNA5SP411 →	+1.023	+2.031	<.001	.007	3	2
HNSC	MIR513C →	+0.517	+7.954	<.001	.008	3	2
SKCM	PPP1R2P6 →	+0.179	+3.788	<.001	.003	3	2
COAD	TRIM48 →	+0.196	+6.392	<.001	.001	3	2
LUAD	PMM2P1 →	+0.063	+4.798	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,798 associations by consensus.

BSNDP1 by CLEC7A expression — BLCA

Explore this box plot interactively →