CLEC7A

Across TCGA cell cohorts, CLEC7A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,430 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLEC7A-associated GO terms across cancer lineages are Positive regulation of cell maturation, Positive regulation of respiratory burst, and Regulation of synapse structural plasticity. Each is linked with CLEC7A in more than 10 cancer types. Because this analysis shows association rather than direction, both CLEC7A-to-partner and partner-to-CLEC7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell maturation grouped by CLEC7A-low versus CLEC7A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC7A→partner) and Y-score (partner→CLEC7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of cell maturation →	-0.339	-1.390	<.001	<.001	2	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of respiratory burst →	-0.234	-2.226	<.001	<.001	3	9
URINARY_TRACT	Regulation of synapse structural plasticity →	-0.880	-1.474	.004	.001	3	9
BREAST	Regulation of mRNA processing →	+0.077	+1.459	<.001	.005	2	9
BLOOD_Myeloma	Detection of fungus →	+2.051	+5.504	<.001	<.001	3	8
BREAST	Negative regulation of RNA catabolic process →	+0.080	+2.109	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,430 associations by consensus.

Positive regulation of cell maturation by CLEC7A expression — OESOPHAGUS

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