Across TCGA pan-cancer cohorts, CLEC5A mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CLEC5A data layer compared with 23 for mass-spec protein and 5 for mutation status.
The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CLEC5A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLEC5A expression acts as an unfavorable survival marker.
PDAC and LUAD are the cancer types where CLEC5A mass-spec protein most reproducibly stratifies survival.