CLEC5A

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CLEC5A mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CLEC5A data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CLEC5A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLEC5A expression acts as an unfavorable survival marker.

PDAC and LUAD are the cancer types where CLEC5A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianAll0.2510.502<.00176view →
LUADDFSMedianAll0.6470.931.0302view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CLEC5A–PDAC (DFS)

Kaplan–Meier survival curve for CLEC5A mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration