CLEC4G

Across TCGA patient cohorts, CLEC4G mutation is significantly associated with the RNA expression of many other genes, with 272 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC4G-associated genes across cancer lineages are MIR6511A1, ACTG1P13, and RNU6-492P. Each is linked with CLEC4G in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4G-to-partner and partner-to-CLEC4G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6511A1 grouped by CLEC4G-low versus CLEC4G-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4G→partner) and Y-score (partner→CLEC4G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6511A1 →	+0.433	+8.471	<.001	.005	3	2
SKCM	ACTG1P13 →	+0.051	+5.508	<.001	<.001	3	2
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	2
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	2
LUAD	ZNF705CP →	+0.300	+5.315	<.001	.003	3	2
UCEC	RN7SL134P →	+0.124	+2.599	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 272 associations by consensus.

MIR6511A1 by CLEC4G expression — BRCA

Explore this box plot interactively →