CLEC4G

Across TCGA cell cohorts, CLEC4G mutation is significantly associated with the RNA expression of many other genes, with 225 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC4G-associated genes across cancer lineages are PPIF, RWDD1, and MRPS15. Each is linked with CLEC4G in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4G-to-partner and partner-to-CLEC4G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPIF grouped by CLEC4G-low versus CLEC4G-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4G→partner) and Y-score (partner→CLEC4G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PPIF →	+0.667	+3.212	.001	.006	3	1
LARGE_INTESTINE	RWDD1 →	+0.492	+3.212	.004	.006	3	1
LARGE_INTESTINE	MRPS15 →	+0.539	+3.299	.001	.004	3	1
LARGE_INTESTINE	IDE →	+0.581	+3.212	.005	.006	3	1
LARGE_INTESTINE	GOT2 →	+0.582	+3.212	.005	.006	3	1
LARGE_INTESTINE	GID4 →	+0.662	+3.299	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 225 associations by consensus.

PPIF by CLEC4G expression — LARGE_INTESTINE

Explore this box plot interactively →