CLEC4F

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLEC4F mutation is significantly associated with the immune_cell of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC4F-associated genes across cancer lineages are Epithelial cells, Th2 cells, and Skeletal muscle. Each is linked with CLEC4F in more than 2 cancer types. Because this analysis shows association rather than direction, both CLEC4F-to-partner and partner-to-CLEC4F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by CLEC4F-low versus CLEC4F-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4F→partner) and Y-score (partner→CLEC4F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADEpithelial cells →-0.096-2.310.004.03623
LUADTh2 cells →+0.212+3.471.009.00232
UCECSkeletal muscle →+0.058+1.600<.001.04332
HNSCPlasma cells →+0.023+2.681.001.02031
UCECEndothelial cells →-0.037-2.205.008.00231
UCEClymphatic Endothelial cells →-0.019-1.866.026.01631
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Epithelial cells by CLEC4F expression — LUAD

Box plot of Epithelial cells in CLEC4F-low vs CLEC4F-high samples in LUAD.

Explore this box plot interactively →

Exploration