CLEC4F

Across TCGA cell cohorts, CLEC4F RNA expression is significantly associated with the go_rna of many other GO terms, with 3,266 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLEC4F-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, RNA splicing, via transesterification reactions, and RNA splicing, via transesterification reactions with bulged adenosine as nucleophile. Each is linked with CLEC4F in more than 12 cancer types. Because this analysis shows association rather than direction, both CLEC4F-to-partner and partner-to-CLEC4F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by CLEC4F-low versus CLEC4F-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4F→partner) and Y-score (partner→CLEC4F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.073	+0.703	<.001	<.001	3	13
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.065	+0.213	<.001	.009	3	11
OESOPHAGUS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.064	+0.213	<.001	.009	3	11
OESOPHAGUS	mRNA splicing, via spliceosome →	+0.064	+0.213	<.001	.009	3	11
BONE	Protein-DNA complex organization →	+0.110	+1.170	<.001	<.001	3	11
LUNG_SCLC	Negative regulation of RNA splicing →	+0.071	+0.599	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,266 associations by consensus.

Negative regulation of gene expression, epigenetic by CLEC4F expression — LUNG_SCLC

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