CLEC4F

Across TCGA cell cohorts, CLEC4F mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CLEC4F-associated genes across cancer lineages are SERPINA7, OR4D6, and MMP26. Each is linked with CLEC4F in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4F-to-partner and partner-to-CLEC4F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by CLEC4F-low versus CLEC4F-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4F→partner) and Y-score (partner→CLEC4F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SERPINA7 →	+0.043	+4.817	<.001	.001	3	2
SOFT_TISSUE	OR4D6 →	+0.023	+3.977	<.001	.007	3	1
SOFT_TISSUE	MMP26 →	+0.072	+3.584	<.001	.004	3	1
SOFT_TISSUE	OR51G2 →	+0.020	+4.369	<.001	<.001	3	1
SOFT_TISSUE	OR52N4 →	+0.065	+3.297	<.001	.008	3	1
STOMACH	LUZP4 →	+0.011	+4.432	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

SERPINA7 by CLEC4F expression — LUNG_SCLC

Explore this box plot interactively →