CLEC4E

Across TCGA patient cohorts, CLEC4E protein abundance is significantly associated with the RNA expression of many other genes, with 1,288 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CLEC4E-associated genes across cancer lineages are CXCL3, FPR2, and PTAR1. Each is linked with CLEC4E in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4E-to-partner and partner-to-CLEC4E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLEC4E versus CXCL3 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4E→partner) and Y-score (partner→CLEC4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CXCL3 →	+1.269	+1.248	.007	.001	3	2
LSCC	FPR2 →	+1.698	+1.611	<.001	<.001	3	2
LUAD	PTAR1 →	-0.597	-0.511	<.001	<.001	3	2
LSCC	MIR298 →	-1.274	-0.866	<.001	.003	3	2
LUAD	YPEL1 →	-0.644	-0.633	<.001	<.001	3	1
LUAD	SOX10 →	-0.411	-0.541	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,288 associations by consensus.

CLEC4E vs CXCL3 — LSCC

Explore this scatter interactively →