CLEC4E

Across TCGA patient cohorts, CLEC4E mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CLEC4E-associated genes across cancer lineages are Erythrocytes, Memory B-cells, and Class-switched memory B-cells. Each is linked with CLEC4E in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4E-to-partner and partner-to-CLEC4E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by CLEC4E-low versus CLEC4E-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4E→partner) and Y-score (partner→CLEC4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Erythrocytes →	+0.055	+3.060	<.001	.039	3	1
SKCM	Memory B-cells →	-0.046	-2.977	.037	.016	3	1
SKCM	Class-switched memory B-cells →	-0.042	-3.268	.024	.007	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Erythrocytes by CLEC4E expression — LUSC

Explore this box plot interactively →