CLEC4E

Across TCGA cell cohorts, CLEC4E RNA expression is significantly associated with the go_rna of many other GO terms, with 450 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLEC4E-associated GO terms across cancer lineages are Steroid catabolic process, Centrosome separation, and Monocyte extravasation. Each is linked with CLEC4E in more than 2 cancer types. Because this analysis shows association rather than direction, both CLEC4E-to-partner and partner-to-CLEC4E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Steroid catabolic process grouped by CLEC4E-low versus CLEC4E-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4E→partner) and Y-score (partner→CLEC4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Steroid catabolic process →	+0.234	+1.756	<.001	.008	3	3
KIDNEY	Centrosome separation →	-0.130	-2.748	.003	<.001	3	3
OVARY	Monocyte extravasation →	+0.850	+1.375	.002	.003	3	3
OVARY	Regulation of macrophage inflammatory protein 1 alpha production →	+0.830	+1.472	<.001	.001	3	2
OVARY	Negative regulation of macrophage inflammatory protein 1 alpha production →	+0.649	+1.428	.001	.002	3	2
KIDNEY	Regulation of platelet aggregation →	+0.137	+3.545	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 450 associations by consensus.

Steroid catabolic process by CLEC4E expression — OVARY

Explore this box plot interactively →