CLEC4E

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CLEC4E mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC4E-associated genes across cancer lineages are BPIFB4. Each is linked with CLEC4E in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4E-to-partner and partner-to-CLEC4E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB4 grouped by CLEC4E-low versus CLEC4E-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4E→partner) and Y-score (partner→CLEC4E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEBPIFB4 →+0.101+4.684<.001.00231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

BPIFB4 by CLEC4E expression — LARGE_INTESTINE

Box plot of BPIFB4 in CLEC4E-low vs CLEC4E-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration