CLEC4D

Across TCGA patient cohorts, CLEC4D protein abundance is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLEC4D-associated genes across cancer lineages are PTK6, PLP2, and LAPTM4B. Each is linked with CLEC4D in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4D-to-partner and partner-to-CLEC4D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLEC4D versus PTK6 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4D→partner) and Y-score (partner→CLEC4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTK6 →	+1.158	+0.815	.003	.006	3	1
LSCC	PLP2 →	+1.035	+0.841	<.001	.002	3	1
LSCC	LAPTM4B →	+1.176	+1.123	.009	.007	3	1
LSCC	P4HA1 →	+1.138	+0.841	.004	.002	3	1
LSCC	PRRG2 →	+1.021	+0.842	.003	.002	3	1
LSCC	POR →	+0.974	+0.842	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

CLEC4D vs PTK6 — LSCC

Explore this scatter interactively →