CLEC4D

Across TCGA patient cohorts, CLEC4D mutation is significantly associated with the RNA expression of many other genes, with 487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC4D-associated genes across cancer lineages are ATP6V0E1P4, LINC02358, and SYF2P1. Each is linked with CLEC4D in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4D-to-partner and partner-to-CLEC4D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V0E1P4 grouped by CLEC4D-low versus CLEC4D-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4D→partner) and Y-score (partner→CLEC4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	ATP6V0E1P4 →	+0.213	+5.266	<.001	.006	3	2
LGG	LINC02358 →	+0.105	+6.135	<.001	.002	3	2
HNSC	SYF2P1 →	+0.140	+5.822	<.001	.003	3	2
BRCA	TSPY18P →	+0.144	+9.057	<.001	.003	3	2
CESC	RNA5SP198 →	+0.284	+5.144	<.001	.003	3	2
COAD	IGHD3-10 →	+1.730	+4.159	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 487 associations by consensus.

ATP6V0E1P4 by CLEC4D expression — LGG

Explore this box plot interactively →