CLEC4A

Across TCGA cell cohorts, CLEC4A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,927 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC4A-associated GO terms across cancer lineages are Cellular response to xenobiotic stimulus, Xenobiotic metabolic process, and Protein sumoylation. Each is linked with CLEC4A in more than 8 cancer types. Because this analysis shows association rather than direction, both CLEC4A-to-partner and partner-to-CLEC4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to xenobiotic stimulus grouped by CLEC4A-low versus CLEC4A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4A→partner) and Y-score (partner→CLEC4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cellular response to xenobiotic stimulus →	-0.075	-0.349	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Xenobiotic metabolic process →	-0.070	-0.209	<.001	<.001	3	7
LARGE_INTESTINE	Protein sumoylation →	+0.041	+0.303	.004	.001	3	7
LARGE_INTESTINE	mRNA 5'-splice site recognition →	+0.101	+0.347	<.001	<.001	3	7
STOMACH	Calcium-independent cell-matrix adhesion →	+0.194	+0.299	.001	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of macroautophagy →	+0.061	+0.262	.006	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,927 associations by consensus.

Cellular response to xenobiotic stimulus by CLEC4A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →