CLEC4A

Across TCGA cell cohorts, CLEC4A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC4A-associated genes across cancer lineages are AVP and PFN3. Each is linked with CLEC4A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4A-to-partner and partner-to-CLEC4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by CLEC4A-low versus CLEC4A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4A→partner) and Y-score (partner→CLEC4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.085	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	PFN3 →	+0.169	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

AVP by CLEC4A expression — LARGE_INTESTINE

Explore this box plot interactively →