Across TCGA pan-cancer cohorts, CLEC3A mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CLEC3A data layer compared with 20 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CLEC3A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLEC3A expression acts as an unfavorable survival marker.
HNSC are the cancer types where CLEC3A mass-spec protein most reproducibly stratifies survival.