CLEC3A

Across TCGA patient cohorts, CLEC3A mutation is significantly associated with the RNA expression of many other genes, with 1,105 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC3A-associated genes across cancer lineages are LINC01050, FCGBP, and TEX30. Each is linked with CLEC3A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC3A-to-partner and partner-to-CLEC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01050 grouped by CLEC3A-low versus CLEC3A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC3A→partner) and Y-score (partner→CLEC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01050 →	+0.188	+2.414	.002	<.001	3	2
UCEC	FCGBP →	-1.313	-2.896	<.001	.002	3	2
SKCM	TEX30 →	+0.642	+1.879	.001	.004	3	2
UCEC	VTI1A →	+0.417	+3.491	.002	.002	3	2
UCEC	CENPU →	+0.706	+3.364	.004	.004	3	2
UCEC	BUB3 →	+0.436	+3.500	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,105 associations by consensus.

LINC01050 by CLEC3A expression — UCEC

Explore this box plot interactively →