CLEC3A

Across TCGA cell cohorts, CLEC3A RNA expression is significantly associated with the go_rna of many other GO terms, with 654 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CLEC3A-associated GO terms across cancer lineages are Regulation of interleukin-1 production, Negative regulation of interleukin-1 production, and Regulation of protein localization to endoplasmic reticulum. Each is linked with CLEC3A in more than 3 cancer types. Because this analysis shows association rather than direction, both CLEC3A-to-partner and partner-to-CLEC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of interleukin-1 production grouped by CLEC3A-low versus CLEC3A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC3A→partner) and Y-score (partner→CLEC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of interleukin-1 production →	-0.113	-2.807	<.001	<.001	3	4
BREAST	Negative regulation of interleukin-1 production →	-0.127	-2.162	.008	.002	3	4
LUNG_SCLC	Regulation of protein localization to endoplasmic reticulum →	+0.055	+0.091	.007	.006	2	4
BREAST	Positive regulation of autophagy →	+0.033	+1.710	<.001	.005	3	3
BREAST	Response to muramyl dipeptide →	-0.139	-2.440	<.001	.001	3	3
BREAST	Regulation of interleukin-1 beta production →	-0.085	-2.231	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 654 associations by consensus.

Regulation of interleukin-1 production by CLEC3A expression — BREAST

Explore this box plot interactively →