CLEC3A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CLEC3A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CLEC3A-associated genes across cancer lineages are URAD and SMIM23. Each is linked with CLEC3A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC3A-to-partner and partner-to-CLEC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, URAD grouped by CLEC3A-low versus CLEC3A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC3A→partner) and Y-score (partner→CLEC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSURAD →+0.022+4.754<.001.00531
BLOOD_LeukemiaSMIM23 →+0.030+6.569<.001<.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

URAD by CLEC3A expression — CNS

Box plot of URAD in CLEC3A-low vs CLEC3A-high samples in CNS.

Explore this box plot interactively →

Exploration