CLEC2L

Across TCGA patient cohorts, CLEC2L mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC2L-associated genes across cancer lineages are RNA5SP419, RNA5SP410, and RNU6-19P. Each is linked with CLEC2L in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC2L-to-partner and partner-to-CLEC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by CLEC2L-low versus CLEC2L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC2L→partner) and Y-score (partner→CLEC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.915	+3.398	<.001	.001	3	2
UCEC	RNA5SP410 →	+0.874	+3.110	<.001	.002	3	2
SKCM	RNU6-19P →	+0.515	+3.856	<.001	.008	3	2
UCEC	EXOC5P1 →	+0.142	+3.653	.002	.005	3	1
UCEC	HMX3 →	+0.964	+3.345	<.001	.001	3	1
UCEC	RNA5SP26 →	+0.223	+4.437	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

RNA5SP419 by CLEC2L expression — UCEC

Explore this box plot interactively →