CLEC2L

Across TCGA cell cohorts, CLEC2L RNA expression is significantly associated with the go_rna of many other GO terms, with 780 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible CLEC2L-associated GO terms across cancer lineages are Transcription initiation-coupled chromatin remodeling, Positive regulation of gene expression, epigenetic, and Nucleic acid catabolic process. Each is linked with CLEC2L in more than 5 cancer types. Because this analysis shows association rather than direction, both CLEC2L-to-partner and partner-to-CLEC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation-coupled chromatin remodeling grouped by CLEC2L-low versus CLEC2L-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC2L→partner) and Y-score (partner→CLEC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transcription initiation-coupled chromatin remodeling →	+0.062	+1.926	.002	<.001	3	6
LUNG_NSCLC_LUSC	Positive regulation of gene expression, epigenetic →	+0.061	+2.151	.004	.006	2	6
SKIN	Nucleic acid catabolic process →	+0.026	+0.511	.001	.003	3	4
SKIN	Regulation of myoblast fusion →	+0.054	+0.732	.002	.004	3	4
LUNG_NSCLC_LUSC	Nuclear RNA surveillance →	+0.071	+2.661	.005	.003	3	4
SOFT_TISSUE	Cellular senescence →	+0.067	+0.535	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 780 associations by consensus.

Transcription initiation-coupled chromatin remodeling by CLEC2L expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →