Across TCGA pan-cancer cohorts, CLEC2A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CLEC2A data layer compared with 17 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CLEC2A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CLEC2A expression acts as an unfavorable survival marker.

UCEC and ESCA are the cancer types where CLEC2A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.224	0.768	.005	12	view →
ESCA	OS	Median	II,III,IV	0.226	0.686	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CLEC2A tumor-vs-normal RNA expression · all CLEC2A data types