CLEC18A

Across TCGA patient cohorts, CLEC18A mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CLEC18A-associated genes across cancer lineages are RN7SL301P, RN7SL790P, and NMNAT1P4. Each is linked with CLEC18A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC18A-to-partner and partner-to-CLEC18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL301P grouped by CLEC18A-low versus CLEC18A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC18A→partner) and Y-score (partner→CLEC18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL301P →	+0.224	+3.809	.006	.007	3	1
SKCM	RN7SL790P →	+0.182	+4.680	<.001	.007	3	1
SKCM	NMNAT1P4 →	+0.061	+6.219	<.001	<.001	3	1
SKCM	HMGN1P14 →	+0.221	+4.993	<.001	.002	3	1
SKCM	RN7SL386P →	+0.148	+4.513	<.001	.009	3	1
UCEC	MIR23C →	+0.755	+3.719	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

RN7SL301P by CLEC18A expression — UCEC

Explore this box plot interactively →