CLEC18A

Across TCGA cell cohorts, CLEC18A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC18A-associated genes across cancer lineages are FTHL17, OR2V2, and OR2J1. Each is linked with CLEC18A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC18A-to-partner and partner-to-CLEC18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTHL17 grouped by CLEC18A-low versus CLEC18A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC18A→partner) and Y-score (partner→CLEC18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FTHL17 →	+0.060	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR2V2 →	+0.025	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR2J1 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	NLRP9 →	+0.227	+4.169	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FTHL17 by CLEC18A expression — LARGE_INTESTINE

Explore this box plot interactively →