Across TCGA patient cohorts, CLEC17A mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CLEC17A-associated genes across cancer lineages are MEK1, STAT3_pY705, and ATM. Each is linked with CLEC17A in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC17A-to-partner and partner-to-CLEC17A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC17A→partner) and Y-score (partner→CLEC17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.490	+3.807	<.001	<.001	3	2
UCEC	STAT3_pY705 →	-0.351	-2.000	<.001	.029	3	2
UCEC	ATM →	-0.542	-3.446	.002	.005	3	2
UCEC	JNK2 →	+0.256	+2.000	.001	.010	3	1
UCEC	Notch1 →	+0.189	+2.000	<.001	.010	3	1
UCEC	p38-MAPK →	-0.130	-2.439	.044	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

CLEC17A survival (RNA) · tumor vs normal (RNA) · all CLEC17A data types