CLEC16A

Across TCGA patient cohorts, CLEC16A mutation is significantly associated with the RNA expression of many other genes, with 4,093 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC16A-associated genes across cancer lineages are RNU6-1213P, BCAS2, and GON7. Each is linked with CLEC16A in more than 3 cancer types. Because this analysis shows association rather than direction, both CLEC16A-to-partner and partner-to-CLEC16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by CLEC16A-low versus CLEC16A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC16A→partner) and Y-score (partner→CLEC16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1213P →	+0.173	+3.985	<.001	.007	3	4
UCEC	BCAS2 →	+0.469	+2.917	<.001	<.001	3	4
UCEC	GON7 →	+0.401	+1.754	.003	.001	3	4
COAD	CEP76 →	+0.504	+3.183	<.001	.009	3	3
UCEC	AAGAB →	+0.502	+1.990	<.001	<.001	3	3
UCEC	KCTD9 →	+0.685	+1.958	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,093 associations by consensus.

RNU6-1213P by CLEC16A expression — BLCA

Explore this box plot interactively →