CLEC16A

Across TCGA cell cohorts, CLEC16A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,121 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLEC16A-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Endosomal transport, and Cytosolic transport. Each is linked with CLEC16A in more than 18 cancer types. Because this analysis shows association rather than direction, both CLEC16A-to-partner and partner-to-CLEC16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagosome maturation grouped by CLEC16A-low versus CLEC16A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC16A→partner) and Y-score (partner→CLEC16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of autophagosome maturation →	+0.146	+0.960	<.001	<.001	3	19
STOMACH	Endosomal transport →	+0.069	+0.986	.001	.007	2	18
STOMACH	Cytosolic transport →	+0.066	+0.925	.001	.001	2	18
URINARY_TRACT	Negative regulation of autophagy →	+0.083	+1.204	<.001	<.001	3	16
OVARY	Vacuolar transport →	+0.065	+0.909	<.001	<.001	3	16
STOMACH	Macroautophagy →	+0.068	+0.873	.005	.009	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,121 associations by consensus.

Negative regulation of autophagosome maturation by CLEC16A expression — BONE

Explore this box plot interactively →