CLEC14A

Across TCGA patient cohorts, CLEC14A protein abundance is significantly associated with the RNA expression of many other genes, with 11,529 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CLEC14A-associated genes across cancer lineages are PEAR1, BCL6B, and PCDH12. Each is linked with CLEC14A in more than 6 cancer types. Because this analysis shows association rather than direction, both CLEC14A-to-partner and partner-to-CLEC14A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLEC14A versus PEAR1 in CCRCC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC14A→partner) and Y-score (partner→CLEC14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PEAR1 →	+0.791	+0.573	<.001	<.001	3	7
CCRCC	BCL6B →	+0.987	+0.573	<.001	<.001	3	6
CCRCC	PCDH12 →	+0.833	+0.625	<.001	<.001	3	5
CCRCC	ROBO4 →	+0.778	+0.556	<.001	<.001	3	5
BRCA	CD34 →	+0.717	+0.472	<.001	<.001	3	5
CCRCC	CDH5 →	+0.874	+0.609	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,529 associations by consensus.

CLEC14A vs PEAR1 — CCRCC

Explore this scatter interactively →