CLEC14A

Across TCGA cell cohorts, CLEC14A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,140 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLEC14A-associated GO terms across cancer lineages are tRNA wobble guanine modification, Regulation of neuron differentiation, and Potassium ion transport. Each is linked with CLEC14A in more than 2 cancer types. Because this analysis shows association rather than direction, both CLEC14A-to-partner and partner-to-CLEC14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble guanine modification grouped by CLEC14A-low versus CLEC14A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC14A→partner) and Y-score (partner→CLEC14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	tRNA wobble guanine modification →	-0.148	-0.003	<.001	.005	3	3
SOFT_TISSUE	Regulation of neuron differentiation →	+0.060	+0.848	<.001	.003	3	3
SOFT_TISSUE	Potassium ion transport →	-0.023	-0.730	.007	.009	3	3
LUNG_NSCLC_LUAD	Synaptic membrane adhesion →	-0.079	-0.007	.001	.002	3	3
LUNG_NSCLC_LUAD	Biogenic amine biosynthetic process →	+0.105	+0.006	.003	.006	3	3
LUNG_NSCLC_LUAD	Biogenic amine metabolic process →	+0.082	+0.005	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,140 associations by consensus.

tRNA wobble guanine modification by CLEC14A expression — KIDNEY

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