CLEC12B

Across TCGA patient cohorts, CLEC12B mutation is significantly associated with the RNA expression of many other genes, with 1,840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLEC12B-associated genes across cancer lineages are RNU6-111P, MIR6803, and HMX2. Each is linked with CLEC12B in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC12B-to-partner and partner-to-CLEC12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-111P grouped by CLEC12B-low versus CLEC12B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC12B→partner) and Y-score (partner→CLEC12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-111P →	+0.330	+5.288	.006	.006	3	2
UCEC	MIR6803 →	+0.161	+4.571	<.001	.002	3	2
UCEC	HMX2 →	+1.121	+3.795	<.001	<.001	3	2
UCEC	IGHD2-2 →	+1.211	+1.819	.002	.008	3	2
UCEC	MLLT10P2 →	+0.179	+2.541	<.001	.007	3	2
LUAD	SPATA31A6 →	+0.011	+4.217	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,840 associations by consensus.

RNU6-111P by CLEC12B expression — BRCA

Explore this box plot interactively →