CLEC12A

Across TCGA patient cohorts, CLEC12A protein abundance is significantly associated with the RNA expression of many other genes, with 5,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLEC12A-associated genes across cancer lineages are CXCR1, CXCR2, and MCEMP1. Each is linked with CLEC12A in more than 3 cancer types. Because this analysis shows association rather than direction, both CLEC12A-to-partner and partner-to-CLEC12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLEC12A versus CXCR1 in PDAC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC12A→partner) and Y-score (partner→CLEC12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CXCR1 →	+1.784	+2.381	.003	.001	3	4
PDAC	CXCR2 →	+1.896	+2.381	<.001	.001	3	4
GBM	MCEMP1 →	+1.057	+0.894	<.001	<.001	3	3
GBM	RSBN1L →	-0.423	-0.698	.003	.006	3	3
GBM	AGK →	-0.549	-1.051	.002	.009	3	3
GBM	MEFV →	+0.856	+0.849	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,848 associations by consensus.

CLEC12A vs CXCR1 — PDAC

Explore this scatter interactively →