CLEC11A

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CLEC11A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CLEC11A data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CLEC11A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLEC11A expression acts as an unfavorable survival marker.

LUAD, LSCC, and PDAC are the cancer types where CLEC11A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileIII,IV0.3330.917.00535view →
LSCCOSQuartileAll0.7040.955.00526view →
PDACDFSMedianIV0.2140.785.0069view →
CCRCCDFSQuartileIII,IV0.0780.740.0387view →
HNSCDFSMedianIV0.5690.779.0281view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CLEC11A–LUAD (DFS)

Kaplan–Meier survival curve for CLEC11A mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration